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AI Clinical RecommendationMargaret Thornton · RE · Visit #18 · 15 May 2026
Awaiting physician decision

Inject Today

Primary Recommendation

Faricimab 6mg intravitreal injection, right eye. Treat-and-extend protocol — maintain 6-week interval pending response.

AI Confidence:94%
Model:RetinoFlow OCT v2.4 + OPHTAI Validation
Generated:15 May 2026 · 21:11
94%conf.

Recurrence Risk Prediction

Probability of fluid recurrence if injection deferred

Longitudinal model · 18-visit history

AI Explainability — Why Inject?

6 contributing factors · OPHTAI validated

DAS of 78 is in the high-activity range (>65). This is the single strongest predictor for injection need. The score incorporates fluid volume, BCVA change, and OCT biomarker severity.

This recommendation was generated by the RetinoFlow OCT Foundation Model (v2.4) and independently validated by the OPHTAI API platform (concordance: 94%). All decisions remain at the discretion of the treating clinician. For CE-marking and SaMD compliance, all AI outputs are logged with full audit trail.

Alternative Pathways

Extend Interval
AI confidence:8%
Risk:Very High

Extension to 8 weeks is not recommended given active SRF/IRF and DAS 78. High probability of further VA decline (estimated −6 to −10 letters over 8 weeks without treatment).

Not Recommended
Maintain & Observe
AI confidence:12%
Risk:High

Observation without injection carries 97% recurrence risk within 4 weeks per longitudinal model. Not clinically appropriate given current biomarker profile.

Not Recommended
Switch to Aflibercept 8mg
AI confidence:31%
Risk:Moderate

Agent switch may be considered if faricimab response remains inadequate after 2 further injections at 6-week intervals. Current evidence supports continuing faricimab unless tachyphylaxis confirmed.

Conditional
Defer 48 Hours
AI confidence:22%
Risk:Low–Moderate

Short deferral acceptable if patient unable to attend today and INR check pending (Warfarin). Reschedule within 48 hours. Risk of significant additional fluid accumulation is low over this period.

Conditional

Physician Decision

Injection Parameters

AgentFaricimab (Vabysmo) 6mg
Dose0.05 mL IVT
EyeRight Eye (RE)
Next visit26 Jun 2026 (6wk)
ProtocolTreat-and-Extend

Audit Trail

15 May 2026

AI recommendation generated

21:11

RetinoFlow AI v2.4

OPHTAI validation completed

21:11

OPHTAI API · 94% concordance

OCT scan analysed

21:09

OCT Foundation Model v2.4

OCT scan acquired

20:44

Heidelberg Spectralis · Technician: R. Patel

Patient checked in

09:32

Reception · Clinic visit #18

Full audit log exportable for MDR/SaMD compliance reporting.